- 商品介绍
- 规格参数
- 包装参数
产品介绍
Product Description
|
规格 |
|
| Accession Number: | NP_005148.2, Y253F |
| Form: | Frozen |
| Kinase Group: | Tyrosine Kinases |
| Protein Form: | Full Length |
| Research Category: | Drug Development |
| Shipping Condition: | Dry Ice |
| Species: | Human |
| Molecular Weight: | 125.4 kDa |
| Gene Alias: | ABL1 Y253F, ABL, c-ABL |
| Validated Application: | Kinase Assay |
| Expression System: | Baculovirus |
| KinaseFamily: | ABL Kinase Family |
| Protein Tag: | His Tag |
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储存 |
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Storage Buffer: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.5 mM EDTA, 0.02% NP-40, 2 mM DTT and 50% glycerol Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws. |
|
描述 |
The ABL1 proto-oncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. The Y253F mutant is a Gleevec resistant form of ABL1.
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