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产品介绍
Product Description
Clone REA1045 recognizes siglec-8, a 54 kDa type I transmembrane protein, which is a member of the Ig superfamily. Though it is mainly expressed by eosinophils, expression of siglec-8 is also found on basophils and mast cells. It has been reported that siglec-8 cross-linking with antibodies reduces eosinophil viability through induction of apoptosis.
Additional information: Clone REA1045 displays negligible binding to Fc receptors.
SAF2, SIGLEC8L
Technical specifications
| 长度(mm) | |
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