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ANTI-HU FOXP3 SET PCH101 FITC SET,71-5776-40,Affymetrix

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订货号 5NW8376
品牌型号 Affymetrix 71-5776-40
货期 询货期
最小订货量 1套
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产品介绍 Product Description
规格
Antigen: Foxp3
Product Line: eBioscience™
Applications: Flow Cytometry
Clone: PCH101
Conjugate: FITC
Format: Conjugated
Gene Alias: Forkhead Box P3, Scurfin, JM2
Host Species: Rat
Isotype: IgG2a
Quantity: Kit
Regulatory Status: RUO
Storage Requirements: Store at 2-8°C. Do not freeze. Light sensitive material. Use within 6 months of opening or by date indicated on the bottle.
Primary or Secondary: Primary
Monoclonal or Polyclonal: Monoclonal
Target Species: Chimpanzee
描述

This Anti-Human Foxp3 Staining Set contains the buffers and monoclonal antibody necessary to successfully stain and identify Foxp3 cells. The PCH101 monoclonal antibody reacts with the amino terminus of human Foxp3 also known as FORKHEAD BOX P3, SCURFIN, and JM2. Foxp3 is a 49-55 kDa protein and a member of the forkhead/winged-helix family of transcription factors. It was identified as the gene responsible for the X-linked lymphoproliferative disease observed in scurfy (sf) mice and in the human disorder, X-linked autoimmunity-allergic dysregulation syndrome (XLAAD). Constitutive expression of Foxp3 mRNA has been shown in CD4+CD25+ regulatory T cells (Treg), and ectopic expression of Foxp3 in CD4+CD25- cells imparts a Treg phenotype in these cells.

The PCH101 antibody crossreacts with rhesus, chimpanzee, and cynomolgus Foxp3 PCH101 recognizes a different epitope of Foxp3 than clones 236A/E7 and 150D/E4.

Isotype
IgG2a, kappa

Laser
Blue Laser

Emit
518 nm

Excite
488 nm

Reported Application
Intracellular Staining Followed by Flow Cytometric Analysis

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