CD11c-VioBright 515, human, REA618, 100t，130-126-883，美天旎

Clone REA618 recognizes the human CD11c antigen, a 145–150 kDa type I transmembrane glycoprotein, which is also known as integrin αX or CR4. It is expressed on monocytes, macrophages, NK cells, granulocytes, myeloid dendritic cells (MDCs), and subsets of T and B cells. On myeloid dendritic cells, CD11c is highly expressed on type 1 myeloid dendritic cells (CD1c (BDCA-1)⁺ CD123^low MDC1s) and low on type 2 myeloid dendritic cells (CD1c (BDCA-1)^– CD123^– MDC2s). CD11c, also known as integrin integrin αX or CR4, has been reported to play a role in adhesion and CTL killing through its interactions with fibrinogen, CD54, and iC3b.

Additional information: Clone REA618 displays negligible binding to Fc receptors.

95, CR4, integrin αX, ITGAX, p150

Technical specifications