CD192 (CCR2) Antibody, anti-human, PE-Vio® 770, REAfinity™，130-127-821，美天旎

Clone REA264 recognizes the CD192 antigen, a G-protein–linked seven transmembrane receptor which is also known as C-C chemokine receptor type 2 (CCR2) or monocyte chemoattractant protein 1 receptor (MCP-1-R). Two spliced variants of CD192 (CD192A and CD192B) are expressed on peripheral monocytes and basophils as a result of alternate splicing of a single gene and differ at the C-terminal end. CD192 and its main ligand CCL2 have been implicated in a wide range of immunobiological processes and neuropathologies, including recruitment of monocytes and regulation of bone marrow homeostasis, as well as multiple sclerosis, HIV-associated dementia, Alzheimer’s disease, and neuropathic pain.

Additional information: Clone REA264 displays negligible binding to Fc receptors.

CCR2, CC-CKR-2, CCR-2A, CCR2B, Ckr2, CKR2A, Ckr2b, Cmkbr2, MCP-1-R

Technical specifications