规格
Activity:	0.008 ng/ml
Bioassay:	Proliferation of B9 cells
Endotoxin Level:	< 0.1 ng/µg
Product Line:	CTS™
Protein Form:	Full Length, Recombinant, Ligand
Purity or Quality Grade:	Carrier-Free
Research Category:	Clinical Research, Bone Research, Stem Cell Research, Immunology, Inflammation
Shipping Condition:	Wet Ice
Species:	Human
Molecular Weight:	21.3 kDa
Purification Method:	Sequential Chromatography
Purity:	95 %
Protein Subtype:	Interleukins
Gene Alias:	IL-6 (Interleukin 6)
Validated Application:	Cell Culture
Protein Family:	Cytokines & Receptors
Expression System:	E. coli
Protein Length:	184 aa

储存
2° to 8° C

描述

Cell Therapy Systems (CTS™) Recombinant Human Interleukin 6 (IL6) is a bioactive protein intended for use in cell culture applications, including pre-clinical and clinical cell therapy studies. IL6 is a pleotropic cytokine involved in several cellular processes including inflammation, hematopoeisis, and immune response. The lyophilized, E. coli-expressed IL6 CTS™ Recombinant Human is verified for activity through dose-dependent proliferation of mouse B9 cells.

• Highly Pure—minimizes interference from other proteins or contaminants
• Active—get more results with less protein

High Purity
To help verify that GIBCO® CTS™ Recombinant growth factors are of the highest quality, each protein is analyzed for purity, along with structural homogeneity, to help ensure a biologically active protein. The purity of each GIBCO® CTS™ recombinant growth factor is verified by SDS-PAGE to be over 95% pure and to have endotoxin levels below 0.1 ng/μg.

High Biological Activity
All GIBCO® CTS™ Recombinant growth factors are verified for activity. Each lot has its own ED50 determined using an activity assay based on a specific function of the growth factor. The activity of our IL6 CTS™ Recombinant Human growth factor is determined by the dose-dependent proliferation of mouse B9 cells to have an ED50 range of 0.008–0.02 ng/mL (specific activity: 1.25 × 10^8–5.0 × 10^7 units/mg). Optimal concentration for individual applications should be determined by a dose response assay.

Related Links
• Learn More About GIBCO® Cell Therapy Systems (CTS™) Products
• Cell Therapy Systems Technical Support Web Page
• Our Full Collection of GIBCO® CTS™ Growth Factors
• Our Full Collection of GIBCO® Growth Factors

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