规格
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Accession Number:
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NP_004603.1 |
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Kinase Group:
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Ser⁄Thr Kinases: TKL Group |
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Shipping Condition:
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Dry Ice |
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Expression System:
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Baculovirus |
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Form:
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Frozen |
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Protein Form:
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Full Length |
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Research Category:
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Drug Development |
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Species:
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Human |
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Validated Application:
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Kinase Assay |
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Molecular Weight:
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62.9 kDa |
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Quantity:
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100μg |
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Gene Alias:
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TGFBR1 (ALK5) |
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KinaseFamily:
|
STKR Kinase Family |
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Protein Tag:
|
GST Tag |
储存
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Kinase proteins are shipped on dry ice and should be stored at -80°C. |
TGFBR1 is a transmembrane serine/threonine kinase in the TGFBR1 superfamily, which also includes ACVRs and BMPRs. Upon binding TGF-b, TGFBR2 dimerizes with and activates TGFBR1 via phosphorylation leading to downstream phosphorylation of SMADs by TGFBR1.