规格
Assay Entry:	Cell-based beta lactamase reporter gene
Cell State:	Dividing Cells
Druggable Target:	Cytokines, Signaling Pathway
Product Line:	CellSensor™
System Type:	CellSensor™
Target Entry:	JAK/STAT (Type I IFN) pathway, TYK2, JAK1

储存
CellSensor® Cell Lines are shipped on dry ice. Store in liquid nitrogen immediately upon receipt, or thaw for immediate use.

描述

Interferon cell signaling is a critical pathway involved in viral defense and autoimmune disease. The CellSensor® ISRE-bla HEK 293T cell line is responsive to interferon alpha and can be used to probe the JAK/STAT signaling pathway.The CellSensor™ ISRE-bla HEK 293T cell line contains the β-lactamase reporter gene under the control of the interferon stimulated response element (ISRE). This cell line was engineered by transduction of the ISRE-bla construct into HEK 293T cells by lentivirus. Flow cytometry was then used to isolate a pool of clones responsive to interferon alpha a stimulation. A dose response curve for this assay against interferon alpha is available in the validation packet. Academic and non-profit customers, please inquire for special pricing.

长度(mm)
宽度(mm)
高度(mm)
重量(kg)