- 商品介绍
- 规格参数
- 包装参数
Clone REAL810 is an antibody fragment derived from the full c-myc antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity.
Clone REAL810 recognizes the multifunctional, nuclear phosphoprotein c-myc, a transcriptional regulator protein, also known as MYC, that is involved in cell cycle progression, apoptosis and cellular transformation. Deregulation including overexpression and mutations of c-myc contributes to the genesis of most human tumors. Expression of c-myc is found in many cancer tissues, e.g. hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma, diffuse large B-cell lymphoma, follicular lymphoma, mantle cell lymphoma, and multiple myeloma.
For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675).
bHLHe39, c-Myc, MYCC
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