规格
|
Accession Number:
|
PPKAA1: NP_006242, PPKAB2: NP_005390, PPKAG3: NP_059127 |
Shipping Condition:
|
Dry Ice |
Expression System:
|
Insect |
Protein Form:
|
Full Length, Recombinant, Active |
Validated Application:
|
Kinase Assay |
Molecular Weight:
|
90.3/56.6/81.4 kDa |
KinaseFamily:
|
CAMKL Kinase Family |
Protein Length:
|
Full Length |
Protein Tag:
|
GST Tag, His Tag |
储存
|
Storage Buffer: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol. |
This AMPK (A1/B2/G3) recombinant human protein (full length) was expressed in insect cells. AMPK (AMP-activated protein kinase) serine/threonine kinase is a heterotrimeric complex, which acts as sensor of cellular energy levels. The signaling cascades initiated by activating AMPK are critical to regulation of metabolic events in the liver, skeletal muscle, heart, adipose tissue, and pancreas. This AMPK consists of the alpha1, beta2 and gamma3 subunits. While the purified AMPK (A1/B2/G3) complex can be used in a number of different applications, it has been specifically validated for use with our Z’-LYTE™ assay technology to identify novel kinase inhibitors. AMPK (A1/B2/G3) recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service.
• Validated for use with the Z’-LYTE™ assay
• Available in multiple pack sizes for convenient use
• Also available in our SelectScreen Kinase Profiling Service