规格
Accession Number:	NP_000052
Assay Entry:	Biochemical phospho-specific activity (no antibody), Biochemical terbium phospho-specific activity, Biochemical europium phospho-specific activity, Biochemical binding/kinetic
Kinase Group:	Tyrosine Kinases
Shipping Condition:	Dry Ice
System Compatibility:	LanthaScreen® Antibody, LanthaScreen® Substrate, Z'-LYTE™, Omnia® Bulk Substrate
Target Entry:	BTK
Target Gene:	Bruton agammaglobulinemia tyrosine kinase
Expression System:	Baculovirus
Protein Family:	Kinases & Inhibitors
Protein Form:	Full Length, Recombinant, Cytoplasmic
Protein Subtype:	Cytoplasmic Tyrosine Kinases
Research Category:	Signal Transduction, Immunology
Species:	Human
Validated Application:	Kinase Assay
Gene ID (Entrez):	695
Molecular Weight:	81.3 kDa
Quantity:	10μg
Gene Alias:	BTK, ATK, XLA
KinaseFamily:	TEC Kinase Family
Protein Tag:	His Tag

储存
Storage Buffer: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.5 mM EDTA, 0.05% Triton X-100, 4 mM DTT, 50% glycerol Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.

描述

Bruton tyrosine kinase (BTK) is a cytoplasmic tyrosine kinase belonging to the SRC-related TEC subfamily of tyrosine kinases. Mutations in the BTK gene have been linked to severe developmental blocks in human B-cell ontogeny and immunodeficiency disorders.

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