规格
Accession Number:	NP_004324.2
Assay Entry:	Biochemical phospho-specific activity (no antibody), Biochemical terbium phospho-specific activity, Biochemical binding/kinetic
Kinase Group:	Ser⁄Thr Kinases: TKL Group
Shipping Condition:	Dry Ice
System Compatibility:	LanthaScreen® Antibody, LanthaScreen® Substrate, Z'-LYTE™, Omnia® Bulk Substrate
Target Entry:	BRAF
Target Gene:	v-raf murine sarcoma viral oncogene homolog B1
Expression System:	Baculovirus
Protein Family:	Kinases & Inhibitors
Protein Form:	Full Length, Recombinant
Protein Subtype:	Serine⁄Threonine Kinases
Research Category:	Oncology, Signal Transduction
Species:	Human
Validated Application:	Kinase Assay
Gene ID (Entrez):	2353, 673
Molecular Weight:	113.6 kDa
Gene Alias:	BRAF, BRAF1
KinaseFamily:	RAF Kinase Family
Protein Tag:	GST Tag

储存
Storage Buffer: 50mM Tris, pH 7.5, 150mM NaCl, 0.5mM EDTA, 0.02% Triton X-100, 2mM DTT, 50% glycerol Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.

描述

BRAF is involved in the transduction of mitogenic signals from the cell membrane to the nucleus. It is activated by somatic point mutation in human cancer, and is thought to play a role in the postsynaptic responses of hippocampal neuron.

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