IL-22 Antibody, anti-human, APC-Vio® 770, REAfinity™，130-130-561，美天旎

Clone REA466 recognizes the human interleukin-22 (IL-22) antigen, a secreted molecule which belongs to the IL-10 family of cytokines. IL-22 is produced by immune cells, including T helper cell subsets and innate lymphocytes, but acts only on non-hematopoietic stromal cells, in particular epithelial cells, keratinocytes, and hepatocytes. It plays an important role in host defense at mucosal surfaces as well as in tissue repair. Although IL-22 is beneficial to the host in many infectious and inflammatory disorders, depending on the target tissue it can be pathogenic due to its inherent pro-inflammatory properties, which are further enhanced when IL-22 is released together with other pro-inflammatory cytokines, in particular IL-17.

Additional information: Clone REA466 displays negligible binding to Fc receptors.

IL-TIF, IL-D110, IL-TIF, ILTIF, TIFIL-23, TIFa, zcyto18, IL-21

Technical specifications