- 商品介绍
- 规格参数
- 包装参数
产品介绍
Product Description
|
规格 |
|
| Antibody Conjugate: | Lanthanide Chelates, Terbium (Tb) |
| Antibody Molecular Weight: | 150000 Da |
| Excitation/Emission: | 340⁄490, 520 |
| Label Type: | Lanthanide Chelates |
| Label or Dye: | Tb (Terbium), GFP (EmGFP) |
| Reactivity: | Human |
| Reactivity abrv: | Hu |
| Readout: | End Point |
| Shipping Condition: | Dry Ice |
| Target Enzyme: | Serine⁄Threonine Kinases |
| Technique: | TR-FRET |
| Validated Kinases: | EIF2AK2, EIF2AK3 |
| Format: | 384-well plate |
| Gene ID (Entrez): | 9833 |
|
储存 |
|
| Terbium-labeled anti-eIF2alpha [pSer52] antibody in HEPES buffered saline. Store at -20°C. |
|
描述 |
The alpha subunit of Eukaryotic initiation factor 2 (eIF2alpha) plays a key regulatory role in protein synthesis. In response to a cellular stress, phosphorylation of eIF2alpha at Ser52 occurs by the EIF2AK family of kinases including PERK (EIF2AK3) and PKR (EIF2AK2) to prohibit the initiation of protein synthesis.
For use in combination with the GFP-EIF2alpha physiological protein substrate (PV4809) to evaluate inhibitors in medium to high throughput screening applications.
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¥ 56581.65
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