规格
Activity:	0.05 ng/ml
Bioassay:	Inhibition of Proliferation of HT2 cells
Endotoxin Level:	< 0.1 ng/µg
Product Line:	CTS™
Protein Form:	Recombinant, Ligand
Purity or Quality Grade:	Carrier-Free
Research Category:	Clinical Research, Neurobiology, Oncology, Stem Cell Research, Cardiovascular Research, Differentiation, Immunology, Bone Research
Shipping Condition:	Approved for shipment at Room Temperature or on Wet or Dry Ice
Species:	Human
Molecular Weight:	25 kDa
Purification Method:	Sequential Chromatography
Purity:	95 %
Protein Subtype:	TGFs (Transforming Growth Factors)
Gene Alias:	TGF-β1
Validated Application:	Cell Culture
Protein Family:	Growth Factors & Receptors
Expression System:	Mammalian
Protein Length:	112 aa

储存
2° to 8°C

描述

Cell Therapy Systems CTS™ Recombinant Human TGF beta 1 (TGFB1) is a bioactive protein intended for use in cell culture applications, including pre-clinical and clinical cell therapy studies. TGFB1 acts synergistically with TGF-α in inducing transformation and acts as a negative autocrine growth factor. Dysregulation of TGFB1 activation and signaling may result in apoptosis. The lyophilized TGFB1 CTS™ Recombinant Human is verified for activity through dose-dependent inhibition of proliferation of mouse HT-2 cells stimulated with mouse IL-4.

• Highly Pure—minimizes interference from other proteins or contaminants
• Active—get more results with less protein

High Purity
To help verify that GIBCO® CTS™ Recombinant growth factors are of the highest quality, each protein is analyzed for purity, along with structural homogeneity, to help ensure a biologically active protein. The purity of each GIBCO® CTS™ recombinant growth factor is verified by SDS-PAGE to be over 95% pure and to have endotoxin levels below 0.1 ng/μg.

High Biological Activity
All GIBCO® CTS™ Recombinant growth factors are verified for activity. Each lot has its own ED50 determined using an activity assay based on a specific function of the growth factor. The activity of our TGFB1 CTS™ Recombinant Human growth factor is determined by the dose-dependent inhibition of proliferation of mouse HT-2 cells stimulated with mouse IL-4 to have an ED50 ≤0.2ng/mL. Optimal concentration for individual applications should be determined by a dose response assay.

Related Links
• Learn More About GIBCO® Cell Therapy Systems (CTS™) Products
• Cell Therapy Systems Technical Support Web Page
• Our Full Collection of GIBCO® CTS™ Growth Factors
• Our Full Collection of GIBCO® Growth Factors

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