CD178 pure, human, REA1056, 0,1ml，130-126-491，美天旎

Clone REA1056 recognizes the CD178 antigen, a type II transmembrane glycoprotein also known as Fas ligand or CD95L. It is expressed on activated lymphocytes, e.g., T cells, NK cells, monocytes, or granulocytes, as well as at immune-privileged sites, e.g., cornea or testis. CD178 can trigger apoptosis through trimerization of the Fas receptor CD95. Thereby, CD178 and CD95 play a key role in the regulation of the immune system. Cleavage of membrane-bound CD178 from the cell surface via matrix metalloproteinases (such as MMP-7) generates soluble CD178 molecules.

Additional information: Clone REA1056 displays negligible binding to Fc receptors.

FASLG, ALPS1B, APT1LG1, APTL, CD95L, FasL, TNFSF6

Technical specifications