规格
|
Accession Number:
|
NP_004603.1 |
Assay Entry:
|
Biochemical binding/kinetic |
Form:
|
Frozen |
Kinase Group:
|
Ser⁄Thr Kinases: TKL Group |
Protein Form:
|
Full Length |
Research Category:
|
Signal Transduction |
Shipping Condition:
|
Dry Ice |
Species:
|
Human |
System Compatibility:
|
LanthaScreen® |
Tag Position:
|
N-Terminal |
Target Entry:
|
TGFBR1 |
Target Gene:
|
TGFBR1 |
Gene ID (Entrez):
|
TGFBR1 |
Molecular Weight:
|
62.9 kDa |
Quantity:
|
10μg |
Protein Subtype:
|
Serine⁄Threonine Kinases |
Gene Alias:
|
TGFBR1 (ALK5) |
Validated Application:
|
Kinase Assay |
Protein Family:
|
Kinases & Inhibitors |
Expression System:
|
Baculovirus |
KinaseFamily:
|
STKR Kinase Family |
Protein Length:
|
aa 200-503 |
Protein Tag:
|
GST Tag |
储存
|
Kinase proteins are shipped on dry ice and should be stored at -80°C. |
TGFBR1 is a transmembrane serine/threonine kinase in the TGFBR1 superfamily, which also includes ACVRs and BMPRs. Upon binding TGF-b, TGFBR2 dimerizes with and activates TGFBR1 via phosphorylation leading to downstream phosphorylation of SMADs by TGFBR1.