Dectin-2 Antibody, anti-mouse, FITC，130-125-214，美天旎

Clone KVa7-6E7 specifically recognizes mouse dendritic cell–associated C-type lectin 2 (Dectin-2). Dectin-2 is a type II membrane protein and contains a single carbohydrate recognition domain. Like other C-type lectins, mouse Dectin-2 has conserved motifs for the Ca²⁺-dependent recognition of mannose. Dectin-2 is located in the natural killer gene complex of chromosome 6. Genomic analyses show that beside a full length Dectin-2 transcript two truncated isoforms are produced by alternative splicing, encoding transmembrane proteins of 168–209 amino acids.¹^,² The expression of Dectin-2 on mouse monocytes and macrophages can be induced by zymosan and thioglycollate.³ Dectin-2 plays a physiological role in antigen presentation and antigen targeting via Dectin-2 can induce a CD8⁺ T cell response.⁴

CLEC4N, Clec6a, Clecsf10, Nkcl

Technical specifications