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LRRK2 I2020T 10 UG,PV5854,Invitrogen

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订货号 3VT5771
品牌型号 Invitrogen PV5854
货期 询货期
最小订货量 1套
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产品介绍 Product Description
规格
Accession Number: NP_940980.2
Assay Entry: Biochemical terbium phospho-specific activity, Biochemical binding/kinetic
Form: Frozen
Kinase Group: Ser⁄Thr Kinases: TKL Group
Protein Form: Catalytic
Research Category: Signal Transduction, Neurobiology
Shipping Condition: Dry Ice
Species: Human
System Compatibility: LanthaScreen®, Adapta™
Tag Position: N-Terminal
Target Entry: LRRK2 I2020T
Target Gene: LRRK2 I2020T
Molecular Weight: 205 kDa
Protein Subtype: Serine⁄Threonine Kinases
Gene Alias: LRRK2 I2020T
Validated Application: Kinase Assay
Protein Family: Kinases & Inhibitors
Expression System: Baculovirus
KinaseFamily: LRRK Kinase Family
Protein Tag: GST Tag
储存
Kinase proteins are shipped on dry ice and should be stored at -80°C.
描述

LRRK2 is a multidomain protein that includes a kinase domain, a GTPase domain, and a leucine-rich repeat (LRR) domain. Mutations in this gene have been associated with Parkinson's disease, including the I2020T mutation in the kinase catalytic domain.

Related Links:
• LRRK2 tools for advancing Parkinson's disease research
• Kinase protein portfolio
• LanthaScreen® Eu Kinase Binding Assay
• LanthaScreen® Activity Assay

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