CD1c (BDCA-1) Antibody, anti-human, FITC, REAdye_lease™，130-127-024，美天旎

Clone REAL1005 is an antibody fragment derived from the full CD1c (BDCA-1) antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity.

Clone REAL1005 recognizes the human CD1c antigen, also known as BDCA-1. CD1c is expressed on a major subpopulation of human myeloid dendritic cells (about 0.3% of blood leukocytes). CD1c (BDCA-1) expression has also been detected on cortical thymocytes, on Langerhans cells, and on CD1a⁺ dendritic cells generated ex vivo from monocytes or hematopoietic precursor cells. CD1c (BDCA-1)⁺ myeloid dendritic cells have been designated as type-1 myeloid dendritic cells (MDC1s). The CD1c antigen is a member of the CD1 family of proteins that are structurally related to MHC class I proteins and mediate the presentation of non-peptide antigens to T cells.

For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675).

BDCA-1, CD1, R7, M241, T6, CD1a

Technical specifications