规格
|
Amino Acid Sequence:
|
Fluorescein-EPPLSQEAFADLWKK |
Assay Entry:
|
Biochemical terbium phospho-specific activity |
Detection Method:
|
Fluorescent |
Label or Dye:
|
FITC (Fluorescein) |
Product Line:
|
LanthaScreen® |
Shipping Condition:
|
Dry Ice |
Substrate:
|
Fluorescein-Tb |
Substrate Properties:
|
Peptide-Based Substrate |
Target Entry:
|
DNAPK |
Target Enzyme:
|
Serine⁄Threonine Kinases |
Substrate Type:
|
Kinase Substrate |
Molecular Weight:
|
2118.3 Da |
储存
|
1 mg/mL Fluorescein-p53 (Ser15) peptide substrates in DMSO. Store at -20° C and protect from light. |
A fluorescein-labeled peptide substrate based upon p53 containing Ser15. p53 is phosphorylated at Ser15 by a wide range of kinases including PI3K/AKT pathway kinases such DNA-PK, ATM, and ATR.
For use in combination with the LanthaScreen® Tb-anti-phospho-p53 [pSer15] antibody (PV5130) to evaluate inhibitors in medium to high throughput screening applications.