规格
|
Product Line:
|
GeneBLAzer® |
Shipping Condition:
|
Dry Ice |
Protein Subtype:
|
Other Proteins |
Research Category:
|
Toxicology & Drug Metabolism |
Validated Application:
|
Assay Standard |
储存
|
Store in ultra-cold freezer (-68 to -85°C). |
TEM-1 beta-lactamase is the most widespread enzyme to confer beta-lactam antibiotic resistance to gram-negative bacteria. It is a monomeric protein that requires no metals or cofactors for activity. TEM-1 beta-lactamase efficiently hydrolyzes most penicillin and cephalosporin substrates, including nitrocefin and fluorescent derivates. This protein is intended to be used as a positive control for enzyme-dependent substrate hydrolysis and for use on immunoblots. Other uses include kinetic studies with novel substrates or identification of inhibitors of beta-lactamase as part of an antimicrobial program.