- 商品介绍
- 规格参数
- 包装参数
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规格 |
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| Antibody Conjugate: | Lanthanide Chelates, Terbium (Tb) |
| Antibody Molecular Weight: | 150000 Da |
| Antigen: | Serine/threonine kinase |
| Assay Entry: | Biochemical terbium phospho-specific activity |
| Excitation/Emission: | 340⁄490, 520 |
| Label Type: | Lanthanide Chelates |
| Label or Dye: | Tb (Terbium), GFP (EmGFP) |
| Product Line: | LanthaScreen® |
| Reactivity: | Human |
| Reactivity abrv: | Hu |
| Readout: | End Point |
| Shipping Condition: | Dry Ice |
| Target Entry: | EIF2AK1, EIF2AK2, EIF2AK3 |
| Target Enzyme: | Serine⁄Threonine Kinases |
| Technique: | TR-FRET |
| Validated Kinases: | EIF2AK2, EIF2AK3 |
| Applications: | Biochemical Kinase Assays |
| Conjugate: | GFP (EmGFP), Tb (Terbium) |
| Format: | 384-well plate |
| Gene Alias: | HPK38, KIAA017 |
| Quantity: | 25μg |
| Regulatory Status: | RUO |
| Storage Requirements: | –20 |
| Type: | Primary |
| Primary or Secondary: | Primary |
| Gene ID (Entrez): | 9833 |
| Packaging: | 1 Each |
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储存 |
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| Terbium-labeled anti-eIF2alpha [pSer52] antibody in HEPES buffered saline. Store at -20°C. |
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描述 |
The alpha subunit of Eukaryotic initiation factor 2 (eIF2alpha) plays a key regulatory role in protein synthesis. In response to a cellular stress, phosphorylation of eIF2alpha at Ser52 occurs by the EIF2AK family of kinases including PERK (EIF2AK3) and PKR (EIF2AK2) to prohibit the initiation of protein synthesis.
For use in combination with the GFP-EIF2alpha physiological protein substrate (PV4809) to evaluate inhibitors in medium to high throughput screening applications.
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瓶顶过滤器-500ml容量,MF75TM系列，聚苯乙烯外壳，75mmPES滤膜，孔径0.45um,适合瓶颈尺寸33mm，12/箱，295-3345，Nalgene，Thermofisher，赛默飞世尔询价
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