规格
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Antibody Conjugate:
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Lanthanide Chelates, Terbium (Tb) |
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Antibody Molecular Weight:
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150000 Da |
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Excitation/Emission:
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340⁄490, 520 |
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Label Type:
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Lanthanide Chelates |
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Label or Dye:
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Tb (Terbium), FITC (Fluorescein) |
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Product Line:
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LanthaScreen® |
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Reactivity:
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Human |
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Reactivity abrv:
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Hu |
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Readout:
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End Point |
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Shipping Condition:
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Dry Ice |
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Target Enzyme:
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Serine⁄Threonine Kinases |
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Technique:
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TR-FRET |
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Validated Kinases:
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CHUK, GRK5, GRK6, IKBKB, IKBKE |
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Format:
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384-well plate |
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Gene ID (Entrez):
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1147, 2869, 3551 |
储存
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|
Terbium-labeled anti-IkappaBalpha [pSer32] antibody in HEPES buffered saline. Store at -20°C. |
An essential component of the canonical NF-kB pathway, phosphorylation of IkappaBalpha at Ser32 by IKK preceedes the transactivation of NF-kappaB.
For use in combination with the Fluorescein-IKK peptide substrate (PV3507) to evaluate inhibitors in medium to high throughput screening applications.