规格
|
Antibody Conjugate:
|
Lanthanide Chelates, Terbium (Tb) |
Excitation/Emission:
|
340⁄490, 520 |
Label Type:
|
Lanthanide Chelates |
Label or Dye:
|
Tb (Terbium) |
Product Line:
|
LanthaScreen® |
Reactivity:
|
Human |
Reactivity abrv:
|
Hu |
Readout:
|
End Point |
Shipping Condition:
|
Dry Ice |
Target Gene:
|
Ser/Thr Kinases |
储存
|
Terbium-labeled pERM (pLRRKtide) antibody in HEPES buffered saline. Store at -20°C. |
A phospho specific antibody directed to the ezrin⁄radixin⁄moesin (ERM) peptide that is a substrate for LRRK2 (Leucine-rich repeat kinase 2) and LRRK2 mutants. Mutations in LRRK2 have been found to be related to late-onset Parkinson's disease.
For use in combination with the Fluorescein-ERM (LRRKtide) substrate (PV4901) to evaluate inhibitors in medium to high throughput screening applications.