规格
Accession Number:	AAI30278
Protein Form:	Recombinant, Active, Catalytic
Shipping Condition:	Dry Ice
Molecular Weight:	110 kDa
Validated Application:	Kinase Assay
Expression System:	Insect
KinaseFamily:	PI3 Kinase
Protein Length:	aa 468 - 1203
Protein Tag:	GST Tag

储存
Storage Buffer: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.

描述

This PIK3C2G (PI3K-C2 gamma) recombinant human protein (468–1203) was expressed in insect cells. PIK3C2G lipid kinase belongs to the phosphoinositide 3-kinase (PI3K) family which play major roles in signaling pathways and are involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. PIK3C2G contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases that act as calcium-dependent phospholipid binding motifs which mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The N-terminal region of PIK3C2G and the C-terminal C2 domain are required for enzymatic activity. PIK3C2G (PI3K-C2 gamma) recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service.

• Validated for use with the Adapta™ assay
• Available in multiple pack sizes for convenient use
• Also available in our SelectScreen Kinase Profiling Service

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