规格
Accession Number:	NP_000450
Assay Entry:	Biochemical phospho-specific activity (no antibody), Biochemical terbium phospho-specific activity, Biochemical europium phospho-specific activity, Biochemical binding/kinetic
Kinase Group:	Tyrosine Kinases
Protein Form:	Recombinant, Cytoplasmic
Research Category:	Signal Transduction
Shipping Condition:	Dry Ice
Species:	Human
System Compatibility:	LanthaScreen® Antibody, LanthaScreen® Substrate, Z'-LYTE™, Omnia® Bulk Substrate
Target Entry:	TEK
Target Gene:	TEK tyrosine kinase, endothelial
Gene ID (Entrez):	7010, 7124
Molecular Weight:	61.5 kDa
Quantity:	10μg
Protein Subtype:	Receptor Tyrosine Kinases
Gene Alias:	TEK (Tie2)
Validated Application:	Kinase Assay
Protein Family:	Kinases & Inhibitors
Expression System:	Baculovirus
KinaseFamily:	TIE Kinase Family
Protein Length:	aa 817-1101
Protein Tag:	GST Tag

储存
Storage Buffer: 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.5mM EDTA, 0.02% Triton X-100, 2mM DTT, 50% glycerol Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.

描述

The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells. TEK signaling appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis, and defects in TEK are associated with inherited venous malformations.

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