规格
|
Antibody Conjugate:
|
Lanthanide Chelates, Terbium (Tb) |
Antibody Molecular Weight:
|
150000 Da |
Excitation/Emission:
|
340⁄490, 520 |
Label Type:
|
Lanthanide Chelates |
Label or Dye:
|
Tb (Terbium), FITC (Fluorescein) |
Product Line:
|
LanthaScreen® |
Reactivity:
|
Human |
Reactivity abrv:
|
Hu |
Readout:
|
End Point |
Shipping Condition:
|
Dry Ice |
Target Enzyme:
|
Serine⁄Threonine Kinases |
Technique:
|
TR-FRET |
Format:
|
384-well plate |
储存
|
Terbium-labeled anti-phospho-p53 [pSer15] antibody in HEPES buffered saline. Store at -20°C. |
The p53 tumor suppressor protein is an essential component of many different signaling pathways. The LanthaScreen® antibody detects the phosphorylation of p53 at Ser15 by a range of kinases including DNA-PK, ATM, and ATR.
For use in combination with the Fluorescein-p53 (Ser15) peptide substrate (PV5132) to evaluate inhibitors in medium to high throughput screening applications.