- 商品介绍
- 规格参数
- 包装参数
Clone REAL1474 is an antibody fragment derived from the full CD4 antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity.
Clone REAL103 recognizes the human CD4 antigen, a 55 kDa Single-pass type I membrane protein also known as T4/Leu-3. CD4 is highly expressed on T helper cells and at a lower level on monocytes and dendritic cells. It is involved in the recognition of MHC class II/peptide complexes by the TCR heterodimers and is the receptor for the human immunodeficiency virus (HIV). CD4 is used in the immunophenotyping of reactive lymphocytes and lymphoproliferative disorders and functions as a marker for post-thymic T cell neoplasms, which have a CD4+ CD8- phenotype.
For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675).
T4, Leu-3, CD4mut, L3T4
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