MACS GMP CD28 pure，170-076-117，美天旎

MACS GMP CD28 pure is a GMP-grade soluble CD28 antibody for ex vivo T cell activation.

The CD28 antibody recognizes the human CD28 antigen which is expressed on T cells and plasma cells. The binding of CD28 to its ligands CD80 and CD86 transfers a costimulatory signal to the T cell.

Activation and proliferation of T cells can be induced by interaction of the T cell receptor (TCR) with peptide-MHC complexes expressed on the surface of antigen presenting cells (APC). T cell activation can also be achieved by agonistic stimulation with the CD3 antibody binding to the TCR complex and can be enhanced by costimulation with CD28 antibody.

The antibody is suitable for ex vivo T cell activation and expansion and can be used in combination with MACS GMP CD3 pure for optimal T cell stimulation towards clinical applications¹.

MACS GMP Products are manufactured and tested under a quality management system (ISO 13485) and are in compliance with relevant GMP guidelines. They are designed following the recommendations of USP <1043> on ancillary materials.

MACS GMP Products are for ex vivo cell processing only, and are not intended for human in vivo applications. For regulatory status in the USA, please contact your local representative.