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产品介绍
Product Description
The monoclonal antibody 6D4 recognizes MICA and MICB, which are transmembrane glycoproteins related to major histocompatibility complex (MHC) class I molecules. In contrast to other MHC class I proteins, MICA/B have no association with β2-microglobulin and do not bind peptides. They are ligands for NKG2D, which is expressed on NK cells and many T cells. MICA/B are expressed on endothelial cells and fibroblasts and are stress-induced in epithelial cells.
MICB, PERB11.2, MICA, PERB11.1
Technical specifications
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