CD158e/k (KIR3DL1/DL2) Antibody, anti-human, pure, REAfinity™，130-126-489，美天旎

Clone REA970 recognizes the human CD158e (KIR3DL1) and CD158k (KIR3DL2) antigens, members of the killer immunoglobulin-like receptor (KIR) family which recognizes subsets of HLA alleles. The family of KIR contributes to the regulation of NK cell–mediated cytotoxicity. Expression is found mainly on CD56^dimCD16⁺ natural killer (NK) cells but also on a subset of CD8⁺ T cells. They are monomeric receptors possessing high allelic polymorphism with either two or three Ig-like extracellular domains. According to the length of their cytoplasmic tail, KIRs can be subdivided in inhibitory KIRs and activating KIRs.

Additional information: Clone REA970 displays negligible binding to Fc receptors.

KIR3DL1, KIR3DL2

Technical specifications