规格
|
Accession Number:
|
PRKAA1: NP_006242.4, PRKAB2: NP_005390.1, PRKAG2: NP_001035723.1 |
Shipping Condition:
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Dry Ice |
Expression System:
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Insect |
Protein Form:
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Full Length, Recombinant, Active |
Validated Application:
|
Kinase Assay |
Molecular Weight:
|
90.3/56.6/85.6 kDa |
KinaseFamily:
|
CAMKL Kinase Family |
Protein Length:
|
Full Length |
Protein Tag:
|
GST Tag, His Tag |
储存
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Storage Buffer: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol. |
This AMPK (A1/B2/G2) recombinant human protein (full length) was expressed in insect cells. AMPK (A1/B2/G2) serine/threonine kinase or AMP-activated protein kinase (AMPK) exhibits a key role as a master regulator of cellular energy homeostasis. AMPK exists as a heterotrimeric complex composed of a catalytic alpha subunit and regulatory beta and gamma subunits. Binding of AMP to the gamma subunit allosterically activates the complex. AMPK is activated in response to stresses that deplete cellular ATP (low glucose, hypoxia and ischemia) and via signaling pathways in response to adiponectin, leptin and CAMKK beta. AMPK (A1/B2/G2) recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service.
• Validated for use with the Z’-LYTE™ assay
• Available in multiple pack sizes for convenient use
• Also available in our SelectScreen Kinase Profiling Service