Nestin Antibody, anti-human, Vio® B515, REAdye_lease™，130-132-500，美天旎

Clone REAL1417 is an antibody fragment derived from the full Nestin antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity.

Clone REAL1417 recognites Nestin, also known as NES, which belongs to the intermediate filament family, forms heterodimers with vimentin or internexin and participating in the remodeling of the cell. Nestin is expressed in a variety of stem or progenitor cells as well as in several types of malignancies. It is required for brain and eye development and is found to be expressed on vascular endothelial progenitor cells and various neoplasms. It is proposed to be a novel angiogenesis marker and cancer therapeutic target.

For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675).

NES

Technical specifications