规格
Endotoxin Level:	< 0.1 ng/µg
Form:	Lyophilized
Mass:	10 µg
Product Line:	Gibco®
Protein Form:	Recombinant, Ligand
Purity or Quality Grade:	Carrier-Free
Reactivity:	Human
Research Category:	Oncology, Signal Transduction
Shipping Condition:	Wet Ice
Species:	Human
Specific Activity:	Linear range of 0.3 to 40 ng⁄ml
Molecular Weight:	42 kDa
Purification Method:	Sequential Chromatography
Purity:	>95% by SDS-PAGE
Quantity:	10μg
Protein Subtype:	Other Proteins
Gene Alias:	DKK-1
Validated Application:	Cell Culture
Protein Family:	Cytokines & Receptors
Expression System:	Mammalian
Biological Activity:	Linear range of 0.3 to 40 ng⁄ml

储存
Store lyophilized human DKK1 at 2 to 8°C, preferably desiccated. Upon reconstitution, apportion into working aliquots and store at ≤ -20°C. Avoid repeated freeze⁄thaw cycles.

描述

Recombinant Human Dickkopf Homolog 1 (DKK1) is a bioactive protein intended for use in cell culture applications. DKK1 is a member of the dickkopf family. It is a secreted protein with two cysteine-rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway.

• High purity—no interference from other proteins or contaminants
• High biological activity—more results with less protein
• Proven compatibility—Gibco® proteins bioassayed with Gibco® media

High Purity Recombinant Bioactive Protein
Recombinant Human Dickkopf Homolog 1 is one of our more than 250 available Gibco® recombinant proteins. To help ensure Gibco® growth factors are of the highest quality, each protein is analyzed for purity along with structural homogeneity to ensure a biologically active protein.

High Biological Activity
In-house activity testing of Gibco® Recombinant Proteins includes cell proliferation, cytotoxicity, chemotaxis, calcium flux, secondary cytokine up-regulation, induction of surface antigen expression, antiviral, and protease assays. Recombinant Human Dickkopf Homolog 1 (DKK1) specific activity is determined by a functional ELISA measuring the ability of human DKK1 to bind immobilized recombinant human LRP6/Fc chimera receptor.

Proven Compatibility
Gibco® proteins are bioassayed with Gibco® media. Since 1962, Gibco® has been the consistent provider of high quality media, reagents, and sera for reliable cell culture.

See our selection of recombinant Gibco® growth factors.

For Research Use Only. Not intended for animal or human diagnostic or therapeutic use.

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