规格
|
Accession Number:
|
NP_068713.2 |
Protein Form:
|
Recombinant, Active, Cytoplasmic, Truncated |
Research Category:
|
Drug Development |
Shipping Condition:
|
Dry Ice |
Species:
|
Human |
Molecular Weight:
|
48.3 kDa |
Gene Alias:
|
JTK11, UFO |
Validated Application:
|
Kinase Assay |
Expression System:
|
Insect |
KinaseFamily:
|
AXL Kinase Family |
Protein Length:
|
473 - end |
Protein Tag:
|
His Tag |
储存
|
Storage Buffer: 50 mM sodium phosphate, pH 7.0, 300 mM NaCl, 150 mM imidazole, 0.1 mM PMSF, 0.2 mM DTT, 25% glycerol
Store at -80°C. Upon first use, aliquot and store at -80°C to avoid multiple freeze/thaws. |
AXL is a chronic myelogenous leukemia-associated oncogene that is also associated with colon cancer and melanoma. The AXL protein is a receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6, and is involved in the stimulation of cell proliferation.
The purified recombinant protein can be used in a number of different applications, but it has been specifically validated for use with both the LanthaScreen™ & Z'-LYTE™ assay technologies to identify novel kinase inhibitors. AXL is also available in our SelectScreen™ Kinase Profiling Service.
• Validated for use with the LanthaScreen & Z'-LYTE assay technology
• Available in multiple pack sizes for convenient use
• Also available in our SelectSceen Kinase Profiling Service