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CAMK2G (CAMKII GAMMA) 10 ug,PV6268,Invitrogen

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订货号 2YW9149
品牌型号 Invitrogen PV6268
货期 询货期
最小订货量 1套
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产品介绍 Product Description
规格
Assay Entry: Biochemical binding/kinetic
Kinase Group: Serine/Threonine Kinase
Target Entry: CAMK2G (CaMKII gamma)
Species: Human
Validated Application: Kinase Assay
Molecular Weight: 60.9 kDa
Quantity: 10μg
Protein Length: aa c-terminus. Contains S36P SNP
Protein Tag: GST Tag
储存
Storage Buffer: 50 mM Tris-HCl pH 7.5, 150 mM NaCl, 0.1 mM EGTA, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol

Store at -68 to -85°C. Aliquot at first use to avoid multiple freeze-thaws.
描述

CAMK2G (CaMKII gamma) is a member of the CAMKII family which are ubiquitous serine/threonine protein kinases that have been implicated in diverse effects of hormones and neurotransmitters. CAMK2G has six alternatively spliced variants that encode six different isoforms. Some of these variants have been identified in human tumors. Transgenic mice expressing a partially calcium-independent mutant form of CAMKG showed 1.5- to 2-fold increase in the thymus of these mice, at least in part due to an increase in the life span of double-positive thymocytes. There was an increase in the number of T cells in the secondary lymphoid organs that had acquired an antigen-dependent memory phenotype. Recombinant human CAMK2G (c-terminal truncation) was expressed by baculovirus in Sf9 cells using an N-terminal GST tag.

• Validated in LanthaScreen® Kinase Binding Assay
• Protocols available for simple use and optimized performance
• Multiple pack sizes available for convenient use

Related Product:
LanthaScreen® Eu Kinase Binding Assay

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