- 商品介绍
- 规格参数
- 包装参数
产品介绍
Product Description
|
规格 |
|
| Accession Number: | NP_002603.1 |
| Kinase Group: | Ser⁄Thr Kinases: Atypical |
| Shipping Condition: | Dry Ice |
| Expression System: | Baculovirus |
| Form: | Frozen |
| Protein Form: | Full Length |
| Research Category: | Drug Development |
| Species: | Human |
| Validated Application: | Kinase Assay |
| Molecular Weight: | 73.9 kDa |
| Gene Alias: | PDK-4 (PDKH4) |
| KinaseFamily: | PDHK Kinase Family |
| Protein Tag: | GST Tag |
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储存 |
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50 mM Tris pH 7.5, 150 mM NaCl, 0.02% Trition X-100, 0.5 mM EDTA, 2 mM DTT, 50% Glycerol. Kinase proteins are shipped on dry ice. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws. |
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描述 |
PDK4 (PDHK4), along with the other PDHKs, regulates glucose metabolism by phosphorylating the E1 alpha subunit of the mitochondrial pyruvate dehydrogenase complex. Inhhibition of PDHKs is viewed as a potential therapeutic treament for type II diabetes.
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