REAlease CD115-PE (REAL272) Kit, m，130-122-632，美天旎

Clone REAL272 is an antibody fragment derived from the full CD115 antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAlease Complex to bind markers with high avidity.

Clone REAL272 recognizes the protein tyrosine kinase transmembrane receptor for macrophage colony-stimulating factor (M-CSF), also known as CSF-1 and interleukin 34 (IL-34). CD115 is a single-pass type I membrane protein. Receptor activation induces homo-dimerization, which leads to phosphorylation and ubiquitinylation of intracellular residues. CD115 is expressed on mouse monocytes, macrophages, and osteoclasts, as well as on common dendritic cell precursors and macrophage/dendritic cell precursors.

The REAlease Kits consist of the respective fluorochrome-conjugated REAlease Complexes and the REAlease Support Kit for removal of the REAlease Complexes and optional relabeling with different fluorochrome-conjugated REAlease Complexes.

Csfmr, Fim-2, FMS, M-CSFR, CSF-1R, c-fms

Technical specifications