规格
Assay Entry:	Biochemical binding/kinetic
Kinase Group:	Receptor Tyrosine Kinase
Target Entry:	FGFR1 V561M
Species:	Human
Validated Application:	Kinase Assay
Molecular Weight:	74.0 kDa
Gene Alias:	FLT2, CEK, FLG, KAL2, BFGFR, C-FGR, CD331, N-SAM
Protein Length:	aa 399-822
Protein Tag:	GST Tag

储存
Storage Buffer: 50 mM Tris-HCl pH 7.5, 150 mM NaCl, 0.1 mM EGTA, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol Store at -68 to -85°C. Aliquot at first use to avoid multiple freeze-thaws.

描述

FGFR1 (also known as FLT2) is a member of the Fibroblast Growth Factor Receptor family that constitute a family of four membrane-spanning tyrosine kinases (FGFR1-4) which serve as high-affinity receptors for 17 growth factors (FGF1-17). The FGF Receptor family plays an important role in multiple biological processes, including mesoderm induction and patterning, cell growth and migration, organ formation and bone growth. FGFR1 is alternatively spliced generating multiple splice variants that are differentially expressed during embryo development and in the adult body. Recombinant human FGFR1 (399-822; V561M) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

• Validated in LanthaScreen® Kinase Binding Assay
• Protocols available for simple use and optimized performance
• Multiple pack sizes available for convenient use

Related Product:
LanthaScreen® Eu Kinase Binding Assay

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