- 商品介绍
- 规格参数
- 包装参数
Clone REA1031 recognizes the human HLA-E protein, a member of the human leukocyte antigen family. HLA-E is a non-classical MHC molecule (MHC-Ib) with limited polymorphisms, which is expressed on the cell surface in a heterodimeric complex with β2-microglobulin. HLA-E is ubiquitously expressed and has a specialized role in NK cell recognition. It binds a restricted set of peptides, e.g., derived from other class I leader sequences. The complex is recognized by NKG2A on natural killer (NK) cells. This recognition protects the HLA-E–expressing cell from NK cell killing. Recently HLA-E recognition by a specialised subset of CD8 T cells has been implicated in pathogen recognition as well as autoimmunity.
Additional information: Clone REA1031 displays negligible binding to Fc receptors.
QA1, EA1.2, EA2.1, HLA-6.2, MHC, HLA-E
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无菌，PETG 方形有刻度培养基瓶，带盖，聚对苯二酸乙二醇酯共聚物，天然高密度聚乙烯盖，500毫升容量，每箱40，40/箱，342020-0500，Nalgene，Thermofisher，赛默飞世尔询价
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