规格
|
Assay Entry:
|
Biochemical terbium phospho-specific activity |
Detection Method:
|
Fluorescent |
Label or Dye:
|
GFP (EmGFP) |
Shipping Condition:
|
Dry Ice |
Substrate:
|
STAT1 |
Substrate Properties:
|
Protein-Based Substrate |
Target Entry:
|
JAK1, JAK2 JH1 JH2, JAK2, TYK2, JAK3, JAK2 JH1 JH2 V617F |
Target Enzyme:
|
Tyrosine Kinases |
Validated Kinases:
|
JAK1, JAK2, JAK3, TYK2 |
Substrate Type:
|
Kinase Substrate |
Molecular Weight:
|
116000 Da |
储存
|
GFP-STAT1 protein substrate in 50 mM Tris-HCl pH 7.5, 100 mM NaCl, 10% Glycerol, 1 mM DTT. Store at -80°C. |
STAT1 expressed as a fusion with GFP (Green Fluorescent Protein) to act as a physiological substrate for the Janus family of tyrosine kinases.
For use in combination with the LanthaScreen® Tb-anti-STAT1 [pTyr701] Antibody (PV4844) to evaluate inhibitors in medium to high throughput screening applications.