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产品介绍
Product Description
The monoclonal antibody 5H10-27 recognizes mouse CD49e, also known as integrin α5, which interacts with integrin β1 (CD29) to form the heterodimer VLA-5, the fibronectin receptor. It is expressed on activated T cells, thymocytes, mast cells, and splenic B cells and plays a role in cell-surface mediated signaling and in adhesion. The 5H10-27 antibody has been shown to inhibit VLA-5 mediated functions and promote the stimulation of CD8+ cells in vitro.
ITGA5, FNRA, VLA5
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