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产品介绍
Product Description
规格 |
|
Accession Number: | NP_005804 |
Kinase Group: | Ser⁄Thr Kinases: AGC Group |
Shipping Condition: | Dry Ice |
Expression System: | Baculovirus |
Form: | Frozen |
Protein Form: | Full Length |
Research Category: | Drug Development |
Species: | Human |
Validated Application: | Kinase Assay |
Molecular Weight: | 127.9 kDa |
Gene Alias: | PRKCN (PKD3), PKC nu |
KinaseFamily: | PKN Kinase Family |
Protein Tag: | GST Tag |
储存 |
|
Storage Buffer: 50mM Tris, pH 7.5, 150mM NaCl, 0.5mM EDTA, 0.02% Triton X-100, 2mM DTT, 50% glycerol Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws. |
描述 |
The PKC family of serine⁄threonine kinases, including PRKCN (PKD3), is activated intracellularly by signal transduction pathways. In humans, at least 12 different PKC polypeptides have been identified. These isoforms differ in primary structure, tissue distribution, subcellular localization, mode of action in vitro, response to extracellular signals, and substrate specificity. PKC alpha, beta I, beta II and gamma form the conventional family; their activities are Ca2+- and phospholipid-dependent.
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