MSCA-1 Antibody, anti-human, Vio® Bright V423, REAfinity™，130-131-334，美天旎

Clone REA781 recognizes the human mesenchymal stromal cell antigen-1 (MSCA-1) antigen, a GPI-anchored protein also known as tissue non-specific alkaline phosphatase (TNAP). MSCA-1 was shown to be restricted to mesenchymal stromal cells (MSCs) in the CD271^bright population in bone marrow. These CD271^brightCD45^dim MSCs have a much higher clonogenic capacity compared to the CD271⁺CD45⁺ fraction in bone marrow. Therefore, MSCA-1 is a suitable marker to identify MSCs with a high proliferative potential.

Additional information: Clone REA781 displays negligible binding to Fc receptors.

ALPL, AP-TNAP, APTNAP, HOPS, TNAP, TNSALP

Technical specifications