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PMPI: N-(P-MALEIMIDOPHENYL) I SOCYANATE, 50 MG.,28100,赛默飞世尔

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订货号 1WS1828
品牌型号 赛默飞世尔 28100
货期 询货期
最小订货量 1套
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产品介绍 Product Description
规格
Crosslinker Type: Heterobifunctional
Labeling Method: Chemical Labeling
Product Line: Pierce™
Reactive Moiety: Maleimide, Isocyanate
Spacer: Short
Solubility: DMSO (Dimethylsulfoxide), DMF (Dimethylformamide)
储存
Upon receipt store at 4°C protected from moisture. Product is shipped at ambient temperature.
描述

Thermo Scientific Pierce PMPI is a maleimide-and-isocyanate crosslinker for attaching compounds to sulfhydryl groups (cysteines) after conjugating the linker to hydroxyl groups on a molecule by urethane (carbamate) bonds.

Features of PMPI:

Reactive groups: maleimide and isocyanate
Reactive towards: sulfhydryl and hydroxyl groups
• Short (8.7A), sulfhydryl-to-hydroxyl crosslinker with an aromatic spacer arm (noncleavable)
• Maleimide group reacts with sulfhydryl groups to form stable thioether linkages
• Isocyanate reacts with non-aqueous hydroxyl groups to form carbamate linkage
• Excellent tool for conjugating hydroxyl-containing compounds such as steroids and vitamins
• Targets and reaction solutions must not contain primary amines

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