规格
Accession Number:	NP_891555
Assay Entry:	Biochemical phospho-specific activity (no antibody), Biochemical terbium phospho-specific activity, Biochemical europium phospho-specific activity, Biochemical binding/kinetic
Kinase Group:	Tyrosine Kinases
Shipping Condition:	Dry Ice
System Compatibility:	LanthaScreen® Antibody, LanthaScreen® Substrate, Zin-LYTE™, Omnia® Bulk Substrate
Target Entry:	FLT4
Target Gene:	fms-related tyrosine kinase 4
Expression System:	Baculovirus
Protein Family:	Kinases & Inhibitors
Protein Form:	Recombinant, Cytoplasmic
Protein Subtype:	Receptor Tyrosine Kinases
Research Category:	Angiogenesis, Signal Transduction
Species:	Human
Validated Application:	Kinase Assay
Gene ID (Entrez):	10725, 2324
Molecular Weight:	85.2 kDa
Gene Alias:	FLT4 (VEGFR3), PCL
KinaseFamily:	VEGF Receptors
Protein Length:	aa 800-1297; Q890H, V1128L, H1146R
Protein Tag:	GST Tag

储存
Storage Buffer: 50 mM Tris pH 7.5, 150 mM NaCl, 0.5 mM EDTA, 0.02% Triton X-100, 2 mM DTT, 50% Glycerol Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.

描述

FLT4 (VEGFR3), a receptor tyrosine kinase, is a key regulator of embryonic blood vessel development and adult angiogenesis. This kinase has been implicated in juvenile hemangioma, kaposi sarcoma, lymphangiomas, and hereditary lymphedemia.

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