规格
Accession Number:	NP_002640.2
Assay Entry:	Biochemical binding/kinetic, Biochemical ADP accumulation
Kinase Group:	Lipid Kinases
Shipping Condition:	Dry Ice
System Compatibility:	Adapta™
Target Entry:	PIK3CG
Target Gene:	phosphoinositide-3-kinase, catalytic, gamma polypeptide
Expression System:	Baculovirus
Protein Family:	Kinases & Inhibitors
Protein Form:	Full Length, Recombinant
Protein Subtype:	Lipid Kinases
Research Category:	Signal Transduction
Species:	Human
Validated Application:	Kinase Assay
Gene ID (Entrez):	5294
Molecular Weight:	130.5 kDa
Gene Alias:	PIK3CG (p110 gamma), PI3 Kinase gamma
KinaseFamily:	PI3 Kinase Family
Protein Tag:	His Tag

储存
Storage Buffer: 50mM Tris-HCl pH 7.5, 150mM NaCl, 0.1mM EGTA, 2mM DTT, 10% Glycerol Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.

描述

PIK3CG (p110 gamma) is the sole class IB phosphatidylinositol 3-kinase family member, which along with the class IA family members, generates the important second messenger PIP2. However, unlike the class IA enzymes which signal downstream of receptor tyrosine kinases, PIK3CG primarily signals downstream of GPCRs.

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