规格
Accession Number:	NP_005397
Assay Entry:	Biochemical phospho-specific activity (no antibody), Biochemical terbium phospho-specific activity, Biochemical binding/kinetic
Kinase Group:	Ser⁄Thr Kinases: AGC Group
Shipping Condition:	Dry Ice
System Compatibility:	LanthaScreen® Antibody, LanthaScreen® Substrate, Z'-LYTE™, Omnia® Bulk Substrate
Target Entry:	ROCK1
Target Gene:	Rho-associated, coiled-coil containing protein kinase 1
Expression System:	Baculovirus
Protein Family:	Kinases & Inhibitors
Protein Form:	Recombinant, Catalytic
Protein Subtype:	Serine⁄Threonine Kinases
Research Category:	Oncology, Signal Transduction
Species:	Human
Validated Application:	Kinase Assay
Gene ID (Entrez):	6093
Molecular Weight:	89.7 kDa
Gene Alias:	ROCK1
KinaseFamily:	DMPK Kinase Family
Protein Length:	aa 1-535
Protein Tag:	GST Tag

储存
Storage Buffer: 50mM Tris, pH 7.5, 150mM NaCl, 0.5mM EDTA, 0.02% Triton X-100, 2mM DTT, 50% glycerol Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.

描述

ROCK1 is a serine⁄threonine kinase that regulates cell differentiation and migration. The Rho⁄ROCK pathway is involved in the progression of various human cancers.

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