- 商品介绍
- 规格参数
- 包装参数
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规格 |
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| Accession Number: | NP_003001 |
| Shipping Condition: | Dry Ice |
| Expression System: | Insect |
| Protein Form: | Full Length, Recombinant, Active |
| Validated Application: | Kinase Assay |
| Molecular Weight: | 70.6 kDa |
| KinaseFamily: | MAP Kinases |
| Protein Length: | Full Length |
| Protein Tag: | GST Tag |
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储存 |
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| Storage Buffer: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol. |
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描述 |
This MAP2K4 (MEK4) recombinant human protein (full length) was expressed in insect cells. MAP2K4 (MEK4) serine/threonine kinase (mitogen-activated protein kinase kinase 4) MEK4 or MKK4 is a dual specificity kinase of the STE7 family that phosphorylates and activates JNK1 and -2 as well as p38. MAP2K4 preferentially phosphorylates the tyrosine residue of JNKs. MAP2K4 mediates a variety of physiological and pathophysiological processes such as responses to cellular stresses and inflammatory cytokines. MAP2K4 is important for carcinogenesis; a loss-off-function mutation in MAP2K4 was found in lung and pancreatic tumors. Conversely, a pro-oncogenic role was also found for MAP2K4. MAP2K4 (MEK4) recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service.
• Validated for use with the LanthaScreen™ Eu Kinase Binding assay
• Available in multiple pack sizes for convenient use
• Also available in our SelectScreen Kinase Profiling Service
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NNALGENE 180透明塑料管，透明，柔软，多用，经济，内径 x 外径x壁厚，1/4 x 1/2 x 1/8，英寸，每箱数量50，50/箱，8000-0080，Thermofisher，赛默飞世尔
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¥ 66743.99
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¥ 66363.43
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¥ 402833.12
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